Augusto and Michaela Odone are dealt a cruel blow by fate when their five-year-old son Lorenzo is diagnosed with a rare and incurable disease. But the Odones' persistence and faith leads to an unorthodox cure which saves their boy and re-writes medical history.

• Universal Pictures
• Kennedy Miller Productions
• Nick Nolte
• Susan Sarandon
• Peter Ustinov
• Ann Hearn
• Maduka Steady
• Aaron Jackson
• Laura Linney
• Kathleen Wilhoite